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Injectable Line \\ Testosterones

Testosterone

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Synthetic testosterone was synthesized in 1935 by the German biochemist Adolf Butenandt and Swiss chemist Leopold Ruzicka who both received a Nobel Prize for their work.

Testosterone profile:

Chemical name: 17b-hydroxy-4-androsten-3-one

Formula (base): C19H28O2

Formula, esters

Propionate: C3H6O2

Phenylpropionate: C9H10O2

Enanthate: C7H12O

Cypionate: C8H14O2

Molecular weight (base): 288.43

Molecular Weight, esetrs

Propionate: 74.0792

Phenylpropionate: 132.1592

Enanthate: 130.1864

Cypionate: 132.1184

Release year: 1935

Anabolic activity index: 100 % (reference drug)

Androgenic activity index: 100 %  (reference drug)

Aromatization: yes

Hepatoxity: no

Rout of administration: injections

Effective drug dosage: Men 250-1500 mg/week

Active half-life:

Base – 2 hours;

Propionate ester – 1-1.5 days;

Phenylpropionate  ester – 2-3 days

Enanthate ester – 5-7 days

Cypionate ester – 7-8 days

Detection time: depends on the ester (up to 3 month for long esters)

Benefits:

Increase in recovery abilities;

Increase in muscle mass;

Strong anti-catabolic properties;

Increase in the amount of red blood cells;

Positive effect on nitrogen and phosphorus metabolism;

Improves mood and well-being.

Possible testosterone side effects:

Aromatization and water retention;

Alopecia;

Acne;

High blood pressure;

Virilization in women;

Suppression of HPTA (decrease of endogenous hormone, testicular atrophy, etc.)

Testosterone - description of the drug

Testosterone is the primary male sexual hormone, which directly affects testicles and prostate development, has a large impact on building the muscle tissue, bone density and strength. Moreover, steroid is to a great extent responsible for dozens of functions in human body: common health, well-being, enhanced libido, energy, immunity, preventing Osteoporosis (loss of bone density), and possible protection against heart disease. Maintaining higher hormone levels in elderly men has been shown to improve many parameters that are thought to reduce cardiovascular disease risk, such as increased lean body mass, decreased visceral fat mass, decreased total cholesterol, and glycemic control. It determines not only gender differences, but, for example, regulates the population of thromboxane A2 receptors on megakaryocytes and platelets and hence platelet aggregation in humans. It is responsible for behavior, mood, romantic relationships, as per reports it can impact even carrier choice. The studies report that attention, memory, and spatial ability are key cognitive functions affected by hormone in humans. Preliminary evidence suggests that low hormone levels may be a risk factor for cognitive decline and possibly for dementia of the Alzheimer's type, a key argument in life extension medicine for the use of hoemone in anti-aging therapies.

All steroid forms in a wide sense are the same: active ingredient testosterone + ester attached, which determines release time and duration of the compounds active life. In a nutshell: long esters release the active ingredient into the blood slowly, but provide a stable hormone level for a long time (depending on the compound), without creating peaks.  Due to this property, there is no need to administer injections often. Short esters release the active substance rapidly, creating peaks in blood, but their lifetime is considerably shorter, and thereby frequent injections are required. Esters, as well as the active substance, have their molecular weight:  by short esters it is less then by the long ones, so each milligram of steroid with a short compounds contain more active substance than the longer one.  For example:

100 mg testosterone propionate = 83.72 mg of testosterone + 16.28 mg of propionate. Half-life – 1.5 days.

100 mg testosterone phenylpropionate = 68.57 mg of testosterone + 31.43 mg phenylpropionate. Half-life - 2 days.

100 mg testosterone enanthate = 71.99 mg of testosterone + 28.01 mg enanthate. Half-life – 5-7 days.

100 mg testosterone cypionate = 69.9 mg of testosterone + 30.1 mg cypionate. Half-life - 7-8 days.

Testosterone drug form

Currently the most widely used forms of medication are the following: suspension (pure), propionate, phenyplpropionate, enanthate, cypionate, composite forms (omnadren, sustanon).

Each hormone ester acts in its own way. Testosterone propionate has the shortest active life, so if you are beginner and it`s your first experience, we recommend you to buy testosterone propionate or phenylpropionate, because due to the short active life potential side effects will disappear quickly, what can`t be said about long steroid compounds. If you start injecting Test-E  or Test-C, possible side effects they can cause, will last as long as ester is active in blood.

Test-P injections are made as a rule every day or every other day. Steroid cycle lasts 6-8 weeks. Testosterone enanthate and cypionate cycles shall be run not less than for 10 weeks. On shorter cycles long esters will not be able to expose their full potential. For enanthate and cypionate is one injection every 5-7 days is enough. However, some athletes prefer more frequent injections in order to provide more even hormone level in blood and to avoid dramatic fluctuations. And don`t forget, that steroid aromatizes very easily to estradiol. Independent on the compound you use, keep your estradiol under control by taking aromatase inhibitors (anastrozole preferably). Antiestrogens (SERMs) are in this context not recommended, because they will reduce the cycle efficiency.

In bodybuilding test is considered to be the main compound. Almost all other steroids are actually derivatives from male hormone.  Steroid is highly favored by athletes for its ability to promote strong increases in muscle mass and strength. As a naturally occurring hormone, it remains the most popular anabolic steroid and is typically used as the base of all cycles and stacks.

Testosterone side effects

Furthermore, as we know, anabolic steroids suppress the hypothalamic-pituitary-testicular axis (HPTA) and thereby reduce the production of endogenous hormone. Drug injections on cycle in stack with other compounds provide the lack compensation of the native hormone and thereby prevent many possible side effects. Moreover, while stacking hormone with other anabolic steroids we get a synergistic effect, providing greater increase in muscle mass and strength.

Be aware, that steroid injections inhibit HPTA. For this reason, it is required to carry out after any steroid cycle the post-cycle therapy (PCT), which promotes the fastest HPTA recovery and, accordingly, increase in endogenous hormones. The main component of any PCT is an antiestrogen (clomiphene, toremifene, tamoxifen).

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